CV Lattes
ORCID
Google Scholar Citations
Rede D'Or São Luiz (RDSL). Instituto D'Or de Pesquisa e Ensino (IDOR). Unidade São Paulo (Institutional affiliation from the last research proposal) Birthplace: Brazil
Rodrigo Nalio Ramos in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Colorectal cancer (CRC) has increased in last decades and represents nowadays the second leading cancer in young adults in Brazil and worldwide. Because it has become a public health issue, fundamental scientific questions focusing on the understanding of the early carcinogenic process may considerably contribute to the precocious CRC diagnosis and treatment. Important sensitive elements …
Recently, there has been a rapid expansion in the development of oncology therapeutics products. With significant commercial potential, cell and gene therapies have emerged as a promising advancement in the healthcare area. Immunotherapy with CAR-T cells has shown promising results in the treatment of refractory hematological malignancies. However, the successful application of CAR-T ther…
Colorectal cancer (CRC) is considered the second most lethal tumor type globally. According to world statistics, CRC has been shown to be increasing among young adults (under 50 years old), affecting both sexes. Despite efforts in early detection of the disease, approximately half of the patients receive the diagnosis at advanced stage, highlighting the significant relevance and urgency o…
Macrophages play diverse roles in the body, including modulation of tissue homeostasis, antigen presentation, phagocytosis, and pathogen elimination. There are two main macrophage differentiation pathways: embryonic-derived macrophages, which become tissue-resident, and blood-derived macrophages recruited during inflammatory processes. In the tumor microenvironment, macrophages are one of…
Cell therapy is a branch of immunotherapy that has been growing in recent decades and shows to be a promising strategy to treat tumors. The fastest growing modality in recent years is therapy based on T cells expressing Chimeric Antigen Receptor (CAR-T). Six products of CAR-T have been approved by the FDA (Food and Drug Administration, USA), all for hematological tumors. Despite the succe…
(Only some records are available in English at this moment)
Multiple Myeloma (MM) is characterized by the uncontrolled proliferation of malignant monoclonal plasma cells in the bone marrow, affecting the production of blood cells. New treatment strategies use Natural Killer (NK) cells, mainly due to their ease of manipulation in vitro, generating NK cells with an enhanced profile for tumor control. In the presence of the cytokine combination of IL…
For many years the therapy of neoplastic diseases has been the focus of several research groups around the world. Among these, adoptive cell therapies, where the cells of the own immune system, and their own mechanisms of effects, are used in the possible tumor remission, has been shown to be effective for some tumor types. In recent years, the functionalization of T lymphocytes with Chim…
(Only some records are available in English at this moment)
Colorectal cancer (CRC) is the second most fatal type of cancer worldwide, and the population affected by this disease is becoming increasingly younger, highlighting the urgent need to understand early diagnosis, initial processes, and disease progression. It is known that various myeloid immune cell types, such as macrophages, which make up the tumor microenvironment (TME), can play crit…
Natural Killer (NK) cells are critical components of the innate immune system, recognized for their ability to eliminate tumor cells. However, the limited availability, donor variability, and genetic modification challenges associated with primary NK cells restrict their widespread application in immunotherapy. To overcome these limitations, human induced pluripotent stem cells (hiPSCs) h…
Dendritic cells (DCs) are the main antigen-presenting cells and several studies have shown that the phenotypic and functional state of these cells may reflect the nature of immune responses against different stimuli. The possibility of DCs generation from blood monocytes in vitro allowed large gain in knowledge about these cells and, also, the development of immunotherapy protocols, espec…
| 1 / 1 | Ongoing grants |
| 1 / 1 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 5 / 4 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 14 / 13 | All research grants and scholarships |
| Associated processes | |