Bachelor of Biomedical Sciences (ICB-USP - 2019) with a project held in the Department of Biochemistry, Neuroscience Area, Institute of Chemistry - USP. She is a junior researcher at Pluricell Biotech, whose goal is to develop cell therapies based on pluripotent stem cells, focusing on therapies for patients with congestive heart failure. Has experience in cell culture and molecular biology methods (flow cytometry, western blotting, qPCR) as well as gene expression manipulation (shRNA). (Source: Lattes Curriculum)
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Bipolar disorder (BD) represents a psychiatric condition with a high degree of disability and few diagnostic and treatment tools due to the poorly elucidated biomolecular mechanism and the overlap of symptoms with other disorders, making it extremely important to better understand the pathophysiology of BD. The neurobiological factors involved in this disorder include mechanisms of neuroi…
The Bipolar Disorder (BD) represents an important risk factor for the development of Alzheimer's Disease (AD). Recently, the neurobiological factors involved in this comorbidity were reviewed by our group, and the mechanisms of neuroinflammation, mitocondrial disfunction, excitotoxicity and compromised neurogenesis are some of those factors. Changes in the distribution of neuronal and gli…
The main feature of bipolar disorder is the pathological humor oscillation between mania and depression. Recently, the study of specific neuropsychiatric biomarkers (endophenotypes) has been an important tool for the understanding of many neuropsychiatric disorders. In bipolar disorder, an important endophenotype is the neuronal immaturity of the dentate gyrus, which was already previousl…
Socio-cognitive deficits are common features present in several neurodevelopmental and psychiatric disorders, including schizophrenia. However, the brain mechanisms underlying such social dysfunctions are still poorly understood. Recently, the purinergic system has earned attention, and it is known that the role of purinergic signaling in schizophrenia is mostly related to the effects of …
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