Abstract
²-lactams have been the drug of choice for the treatment of bacterial infection for many decades. However, due in part to the misuse of these antimicrobial agents, drug-resistant bacteria are posing a growing threat to global health. According to the WHO, 9 of the 12 most dangerous families of bacteria are resistant to ²-lactam antibiotics, due to the presence of ²-lactamase enzymes. Prel…