Abstract
More than 95% of the malignant neoplasms of the oral cavity are squamous cell carcinomas (SCCs). Despite advances in the treatment of oral SCC (OSCC), survival after 5 years has remained at less than 50% in the last 40 years. Recent studies have shown that oropharyngeal SCC (OPSCC) has changed its clinicopathological profile and is frequently associated with human papillomavirus (HPV) inf…