PhD* Organic and Biological Chemistry at Institute of São Carlos (IQSC) - University of São Paulo (USP) with a six months internship at the University of Münster, Germany. MSc Organic and Biological Chemistry at Institute of São Carlos (IQSC) - University of São Paulo (USP). BSc Chemistry (Food Chemistry) at the São Carlos Institute of Chemistry (IQSC) - University of São Paulo (USP). (Source: Lattes Curriculum)
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New treatments for neglected tropical diseases are needed, and peptidomimetic compounds, which inhibit cysteine proteases and are more stable than peptides, show great promise as new oral drugs, more effective and with fewer side effects than current treatments. Recent studies have shown that some compounds of this class, despite having great inhibitory activity for enzymes, have not been…
Trypanosoma cruzi is a flagellated parasite that causes Chagas disease. This parasite depends on cruzipain, a cysteine protease essential for its survival. Our research group has identified inhibitors of recombinant cruzain which are tripanosomicide drug candidates for the treatment of Chagas disease. These are dipeptidyl nitriles that inhibit cysteine proteases of the papain family and t…
| 2 / 2 | Completed scholarships in Brazil |
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