Abstract
Post-translational modifications by phosphorylation and s-nitrosylation were detected by proteomic analysis in several key enzymes of cell signaling processes in the parasite when it comes into contact with ECM. Some of these proteins are involved in cAMP, cGMP and calcium-mediated signaling processes, such as cAMP phosphodiesterase (PDE) and calmodulin. This project aims to validate the …