Abstract
The Nox3eqlb mouse is a mutant line with phenotype of lack of motor coordination and equilibrium selected by a mutagenesis project by ENU (ethylnitroso-urea). This mouse shows increased proliferation of granule cell progenitors (GCPs) during postnatal development (up to 15 days of age), as well as a disorganized Purkinje cell layer. Recently, our group identified the mutation that causes …