Abstract
NADPH oxidase 4 (Nox4) is an isoform of NADPH oxidase. This family of enzymes is dedicated to the production of reactive oxygen species (ROS) in cells. It is known that, in melanoma cells, the expression and activity of Nox4 are increased when compared to healthy cells and it may influence the proliferation, migration and survival of malign cells. Since melanoma is the most aggressive typ…