Abstract
The main targets of thematic project are the modulation of macrophages by CSFs to promote the formation of M2 macrophages. These cells produce a series of growth factors, which promote vessel formation and remodeling, and myogenesis in ischemic and inflamed skeletal muscle. The main oxygen sensor in cells is the proline hydroxylase of HIF (Hypoxia Inducible Factor), which is called the PH…