Abstract
Aldosterone (Aldo) is a mineralocorticoid hormone that regulates the renal transport of sodium (Na+) and potassium (K+) ions. However, Aldo has extrarenal effects, especially at supraphysiologic concentrations, which contribute to cardiovascular disease. Aldo, due to its pro-fibrotic, pro-inflammatory and pro-oxidative properties, promotes several changes in target organs, such as the hea…