Abstract
Ibuprofen is is one of the most prescribed non-steroidal anti-inflammatory (NSAID) in pediatric practice . This drug reduces the production of prostaglandins (PGs) through the inhibition of the enzyme cyclooxygenase (COX-1 and COX-2) Recent studies have reported a lot of PG functions in the male gonad, and COX inhibiting drugs may negatively impact the male reproductive system. In additio…