Abstract
The Human Leucocyte Antigen (HLA) genes, located at 6p21.3, are involving in susceptibility to more than 100 diseases of inflammatory, infectious and autoimmune nature. HLA genes are relevant in pharmacogenetics, as several of their alleles are associated with hypersensitivity to specific drugs, such as carbamazepine (CBZ). With a density of SNPs significantly higher than most regions, HL…