Graduated in Biological Sciences from the School of Health Sciences of São Paulo (FACIS). Has experience in the fields of Genetics, Evolution, and Molecular Biology. Completed a scientific initiation internship since the beginning of 2016 at the Laboratory of Drosophilids with Evolutionary Genomics in the Department of Genetics and Evolutionary Biology at the Institute of Biosciences at USP, under the guidance of Prof. Dr. Maria Dulcetti Vibranovski, where she is currently pursuing a Ph.D. in the field of Evolutionary Genomics, with her project focused on RNA-seq data and cytogenetic analyses since 2018. In 2023, she conducted a Sandwich Doctorate at Arizona State University, studying the impact of the X chromosome on male fertility in Drosophila. (Source: Lattes Curriculum)
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Meiotic Sex Chromosome Inactivation (MSCI) is a process of transcriptional silencing of the sex chromosomes in the early stages of meiosis in spermatogenesis. Scientists have investigated the existence and impact of MSCI on D. melanogaster and some aspects related to spermatogenesis raised a great debate about the existence of this mechanism. During the period of the master's degree, the …
Chromosomal sexual differentiation through evolution has resulted in a loss of similarity between sex chromosomes, leading several consequences in the dosage between them and their behavior. During meiosis, these differences trigger a silencing mechanism of these unpaired sex chromosomes, such as Meiotic Sex Chromosome Inactivation (MSCI), which is the process of early transcriptional sil…
Chromosomal Translocations between X and autosomes are a common cause of male infertility in many species, including those from the Drosophila genus. Such a phenomenon is associated in the literature with a regulatory mechanism called Meiotic Sex Chromosome Inactivation (MSCI). Our most recent research has demonstrated that the loss of RNA polymerase II activity during the last phases of …
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