Abstract
Glioblastoma multiforme (GBM) is a cancer originated from the uncontrolled proliferation of astrocyte cells. These cells are the most abundant cell type in the human brain. Several functions are attributed to astrocyte cells, such as: i. A constituent of the blood brain barrier (BBB); ii. Nourish neighboring cells, such neurons; iii. Keep the extracellular ions balance; and iv. Help in th…