Abstract
Parkinson's disease is the second most common neurodegenerative disease. It is characterized by the accumulation of alpha-synuclein in the brain, leading to the formation of Lewy bodies, and by the depletion of nigrostriatal dopaminergic neurons. PD dementia (PDD), in turn, represents one of its most relevant non-motor manifestations and is among the primary sources of stress for caregive…