Abstract
The proposal of this project is use a dual inhibitor (C14) of Epoxy Hydrolase soluble/Fatty Acid Amide Hydrolase (sEH/FAAH), still on a trial basis, on induced nociception in rats temporomandibular joint (TMJ).The epoxieicosatrienoicos acids (EETs) have several biological actions as vasodilators, anti-inflammatories and analgesics, however the EETs are fast metabolized by the enzyme Epoxi…