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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Sidneia Sousa Santos in research grants and scholarships supported by FAPESP.
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Poly(ADP-polymerase)1 (PARP1, the major isoform of a family of poly(ADP-ribosyl)ating enzymes), a constitutive nuclear and mitochondrial enzyme, is a key regulator of DNA repair, cell death and gene expression. In addition to regulating nuclear DNA repair and maintaining genomic integrity, PARP1 functions include: a) regulation of DNA repair, b) regulation of gene transcription, and c) ca…
Poly(ADP-polymerase)1 (PARP1, the major isoform of a family of poly(ADP-ribosyl)ating enzymes), a constitutive enzyme, is a key regulator of DNA repair, cell death and gene expression. Activation of PARP in response to reactive oxidants promotes cell death and pro-inflammatory signalling. Pathophysiological PARP over-activation and the beneficial effects of PARP inhibitors have been demon…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 3 / 3 | All Scholarships |
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