Abstract
Primary Aldosteronism (PA) is the most common form of secondary Hypertension (HT), with a prevalence of approximately 20% in patients with resistant Hypertension. In the last decade, somatic Pathogenic Variantes (PVs) in KCNJ5, CACNA1D, ATP1A1 and ATP2B3 genes, which are involved in maintaining intracellular ionic homeostasis and cell membrane potential, were described in 38%, 9.3%, 5.3% …