Abstract
Germ cell tumors (GCTs) are benign or malignant neoplasms, divided into seminomatous and non-seminomatous, with different levels of differentiation, that can occur in gonadal or extragonadal sites. The GCTs treatment is based on histogenesis tumors, but it is known that the cisplatin treatment has a great relevance when patients' survival is observed. One of the mechanisms related to tumo…