Abstract
This proposal aims to assess the immunogenicity of the antigenic preparations based on OMVs of Neisseria meningitidis B complexed to two different adjuvants, the cationic lipid DODAB-BF and aluminum hydroxide in elderly mice immunized by subcutaneous injection. We will used isogenic mice female BALB/c and/Sn with approximately 360 days of life.To characterize the interaction of antigens …