Abstract
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by muscle weakness, slurred speech, and dysphagia, leading to atrophy and paralysis. It involves more than 20 gene mutations, with C9orf72, SOD1, and TARDBP being the most prevalent. Late onset hinders early diagnosis, as symptoms only appear after approximately 40% of motor neurons are lost. In addition to n…