Mariana Marcela Góis in research grants and scholarships supported by FAPESP.
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PARP-1 is a protein involved in DNA repair, DNA replication, transcription, genome organization and apoptosis. Once activated by DNA damage, PARP proteins are able to post-translation- modify proteins in a process called parylation, using NAD+ as substrate. Several studies have proved the feasibility of the use of PARP inhibitors as adjuvant chemotherapeutic agents for the treatment of Ca…
Genomic instability is a hallmark of cancer characterized by an increased rate of alterations in the genome, which favors tumorigenesis and tumor progression. Luckily, cells have mechanisms such as DNA repair, which respond to the presence of DNA damage and help maintain genomic integrity and stability. Recently, the S6K1 protein, a target of mTORC1, has been linked to DNA repair. Particu…
| 1 / 1 | Ongoing scholarships in Brazil |
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
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