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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Isabella Draszesski Malagó in research grants and scholarships supported by FAPESP.
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In spite of the high incidence of breast cancer, there are few pharmacological strategies available to prevent the development of tumors and recurrences in the high risk population. The available strategies are used systemically and provoke severe adverse effects, like fatigue, reduction of bone density, thromboembolism, cardiovascular symptoms and increased risk of developing other tumor…
Chemoprevention is an important strategy for reduction of breast cancer incidence. However, women's adherence to the currently available strategies is very low mostly because of the severe adverse effects. Our group has been focusing on the development and evaluation of nanocarriers containing drug combinations as potential new strategies for pharmacological prevention of breast cancer. I…
Chemoprevention is a potential strategy for reduction of breast cancer rates worldwide. However, the available pharmacological options with this purpose present several serious adverse effects, which limit women's adherence to treatment. This project aims to develop and characterize a nanostructured lipid carrier for the drug fenretinide, for subcutaneous administration in the mammary tis…
In this project, we propose to develop and evaluate an in situ-forming multifunctional hydrogel for intramammary delivery of fenretinide and a mitogen-activated protein kinase-activated protein kinase-2 inhibitor peptide (YARA) aiming at breast cancer chemoprevention. Due to the low aqueous solubility of fenretinide, we envisioned hydrogels enriched with fenretinide-loaded nanostructured …
| 1 / 1 | Ongoing scholarships in Brazil |
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 4 / 4 | All Scholarships |
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