Abstract
The purpose of the current project is to perform the analysis of the renal miRNA expression profile of Pkd1 (the mutated gene in the Autosomal Dominant Polycystic Kidney Disease - ADPKD) haploinsufficient animal model. ADPKD is the most common renal monogenic disorder with population prevalence from 1:400 to 1:1000. It is characterized by progressive, bilateral renal cystic expansion foll…