Abstract
During high-intensity exercise and systemic hypoxia, the reduction of nitrate ions (NO3-) and nitrite ions (NO2-) into nitric oxide (NO) may contribute to vasodilation, as endothelial nitric oxide synthase exhibits reduced enzymatic activity under lower inspired oxygen fraction, as oxygen is a product. However, the relationships between NO3- and NO2- bioavailability and endothelial functi…