Abstract
The aim of this work will be to compare the effect of Stevia (natural sweetener) to aspartame (synthetic sweetener), sucrose and xylitol on the development of dental caries under microcosm biofilm model in enamel and dentin. Two hundred and sixteen bovine enamel samples and 216 bovine root dentin samples (4 mm x 4 mm) will be prepared. In 24-well plates, each enamel or dentin sample will …