Abstract
Colorectal cancer (CRC) is the third most frequently diagnosed in the world and the second largest cause of cancer death. In Brazil, 36 mil cases were diagnosed in men and the second in women. Among these numbers, in Brazil, 17.284 deaths were recorded for CRC, of which 4.968 were for rectal cancer. A major risk factor for tumor progression is the spread of tumor cells in the blood. Circu…