Student of Biomedicine at Cruzeiro do Sul University (2018).Currently, developing a Scientific Initiation project involving the enteric nervous system of an animal model of type 2 diabetes, in the Interdisciplinary Postgraduate Program in Health Sciences at Universidade Cruzeiro do Sul. (Source: Lattes Curriculum)
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The Goto-Kakizaki (GK) rat spontaneously develops Type 2 Diabetes Mellitus (T2DM) but without obesity. In GK rats, we reported slow intestinal transit and increased small intestinal pro-inflammatory markers. The myenteric plexus is part of the enteric nervous system (ENS) and controls intestinal motility. The myenteric of small intestine pf GK rats has differences regarding the density of…
The association between diabetes mellitus type 2 (DM2), insulin resistance (IR), and obesity is very well established. Under these conditions, a low-grade systemic inflammation is reported that reduces the activity of the insulin signaling pathway. The gastrointestinal tract (GIT) activity is controlled by an intrinsic nerve network, the enteric nervous system (ENS), which is composed of …
Professor Keith A. Sharkey is one of the most globally recognized scientists in intestinal microbiota research. During the BEPE, Gabriela will carry out experiment on the relevance of intestinal microbiota in the diabetic phenotype of Goto-Kakizaki (GK) rats. The GK rat develops type 2 diabetes mellitus (T2DM) spontaneously, without obesity. T2DM causes marked changes in enteric nervous …
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