Abstract
CD4 T lymphocytes are the main target cells of HIV-1. However, myeloid cells can also become infected by HIV-1 through interaction with CD4/CCR5 receptors. Macrophages can survive infected for long periods and present compartments containing viruses (VCCs), where HIV-1 accumulates and remains infective. For these reasons, macrophages may be potential viral reservoirs. On the other hand, d…