Abstract
The binding immunoglobulin protein (BiP) belongs to the class of proteins called molecular chaperones and to the family of 70 kDa heat shock proteins (Hsp70). This macromolecule is mainly found in the endoplasmic reticulum (RE) and acts in the control of cellular proteostasis, interacting with proteins, called client proteins, so that they acquire their native conformation. It has two dom…