Abstract
Chagas' disease is caused by Trypanosoma cruzi and affects 8 million people, mostly in Latin America. In trypanosomatids, including T. cruzi, the presence of a giant protein (PGs) family with high molecular mass (e 500 kDa) has been demonstrated and located at the Flagellar Adhesion Zone (FAZ). This region has the function of connecting the cell body to the flagellum, playing numerous rol…