Abstract
Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease all over the world. This disease affects individuals who develop steatohepatitis (NASH), which can progress to fibrosis in 20 to 40% of cases, with 10% progressing to cirrhosis and 1-5% hepatocellular carcinoma (HCC). In the presence of NASH, hyperinsulinemia, adipose inflammation and hypoadiponectinemia…