Abstract
The TRPV4 are non-noxious temperature-sensitive channels, important to peripheral temperature sensation. It has been described that TRPV4 are expressed in the preoptic area of hypothalamus, a key region involved in thermoregulation. Although ther is evidence of increasing endotoxin-induced TRPV4 expression in hypothalamus of rats, no study has verified the role of these channels in the re…