Abstract
Worldwide, bladder cancer is the seventh most common neoplasia in men and the seventeenth in women, and the urothelial cell carcinoma (UCC) is responsible for approximately 90% of these malignant tumors. The most used and successful chemotherapies for UCC include combinations of methotrexate, vinblastine, doxorubicin and cisplatin (MVAC), or combination of gemcitabine and cisplatin. Commo…