Abstract
Preeclampsia (PE) is a disease that occurs in 2 to 8% of all pregnancies, and is a major cause of maternal and fetal mortality and morbidity. It is a hypertensive disease of pregnancy and can be characterized by an exaggerated production of reactive oxygen species (ROS), generalized inflammatory response, increase of antiangiogenic factors and endothelial dysfunction. Nitric oxide (NO) is…