Abstract
Studies with the bifunctional protein CrataBL have shown that this protein prolongs the partially active thromboplastin test time (aPTT) by influencing the intrinsic coagulation pathway, and in addition it inhibits the effect of heparin on the same pathway suggesting that the interaction of CrataBL with Heparin neutralizes its anticoagulant effects. Contrary to the action of heparin, Crat…