Abstract
The study of sialagogue substances is of clinical interest because of their usefulness in patients with xerostomia. Cholinergic agonists stand out, pilocarpine being one of the most important. It induces salivation, injected peripherally and also water intake. The intracerebroventricular injection (icv) of muscarinic antagonists showed that the salivation produced by pilocarpine injected …