Danilo Chaves da Silva Ramos de Souza

Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

Abstract
CD4+ T cell activity is essential for the development of effective immune responses in various pathological contexts, including infection with parasites of the genus Plasmodium. In secondary lymphoid organs, CD4+ T cells differentiate into two distinct effector lineages: TFH and non-TFH cells. TFH cells proceed to germinal centers where they interact with B cells and assist them in antibo…
Evaluation of the role of IF1 on CD4+ T cell differentiation: possible regulatory action of P2X7 and CD39, BP.MS
Abstract
Malaria is a disease that affects nearly 200 millions of people annually. Understanding the immunological mechanisms, such as the role of Tfh and Tfr cells, that orchestrate Plasmodium response and immunity is essential to develop new parasite strategies control. P2X7 is an extracellular ATP receptor expressed in some cells of immune system; in macrophages and neutrophils, P2X7 activation…
Evaluation of P2X7 influence on caspase-1 activation and GSDMD cleavage in Tfh and Tfr cells in experimental Malária model, BP.IC

Source:Lattes Curriculum

Danilo Chaves da Silva Ramos de Souza

CV Lattes ORCID

2 / 2	Completed scholarships in Brazil

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Abstract

Abstract