Abstract
The role of the mitochondria and endoplasmic reticulum contact site in cellular neurodegeneration emerge new opportunities to uncover the molecular biology underneath ±-Synucleinopathies in dopaminergic cells in the Parkinson's disease. In fact, it has been proved that the ±-Synuclein can alter the morphology of mitochondria and ER and this alteration has an influence on the contact site.…