CV Lattes
ORCID
Abstract
Marfan syndrome (SMF) is an autosomal dominant systemic disease that affects connective tissue due to mutations in the fibrillin-1 gene that cause alteration in fibrillin-1 protein, one of the major microfibril components of the extracellular matrix of connective tissue. Individuals with SMF have lower muscle mass characterized by reduced size and number of muscle fibers and consequent lo…