Graduated with a Bachelor's degree in Biological Sciences from São Paulo State University (UNESP). Currently a Master's student in Biochemistry at the Institute of Chemistry (IQ) of the University of São Paulo (USP), focusing on Molecular Biology and Biochemistry of Trypanosomatids. Research emphasis includes the investigation of cytotoxicity and genotoxicity of thymidine analogues used to monitor DNA replication. Previously conducted undergraduate research projects at the Department of Structural and Functional Biology, Institute of Biosciences of Botucatu (IBB). Experienced in the fields of Trypanosomatid Genetics, with a focus on fluorescent methods for monitoring DNA replication; Structural Biology; Cell Biology and Biochemistry; Developmental Biology; Reproductive Toxicology; and Prostate Carcinogenesis (Source: Lattes Curriculum)
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Thymidine analogs (most common 5-Bromo-22-deoxyuridine - BrdU, and 5-Ethynyl-2'-deoxyuridine - EdU) are widely used to monitor DNA replication in eukaryotic cells. However, recent articles have been reporting certain levels of cytotoxicity in mammalian cells, which can bias data related to the replication capacity of the analyzed cells. In trypanosomatids (unicellular eukaryotic parasites…
Environmental factors have influenced the intrauterine microenvironment, which has had important consequences on late development due to the actuation of these substances as endocrine disruptors. It should be noticed that most of these substances are commonly found in food packaging materials, children's toys, nail polishes, special care products. Phthalates represent a group of ubiquitou…
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