Abstract
Neoplastic cells gain the migratory and invasive phenotype by going through the epithelial-mesenchymal transition (EMT), which involves changes in cell-cell (via cadherins) and cell-matrix (via integrins) contacts. Fibronectin is a major constituent of the extracellular matrix of oral cavity squamous cell carcinoma (OSCC), and its expression level/relative amount is associated with a wors…