Abstract
MicroRNAs (miRNAs) are a wide class of small (~22nt) non-coding RNAs present in the eukaryotic genome that act directly on the developmental control and homeostasis of these organisms. During miRNA biogenesis, cells generate mature transcripts (miRNAs 5p e 3p) capable of coordinating the modulation of gene expression profile in response to the biological context of the organism. The mecha…