Lucas Oliveira holds a bachelor's degree in Computer Science from University Center of Pará (CESUPA) and a master's degree in Computer Science from University of Campinas (UNICAMP). Currently, he is a PhD student in Computer Science at the Institute of Computing (IC), University of Campinas (UNICAMP), focusing on research in Computational Biology. In particular, he works with algorithms and data structures for high-throughput sequencing data in the context of variant detection. He also worked as a bioinformatician at Scylla Informatics, where he collaborated with diverse projects in Bioinformatics. Research interests are mainly Comparative Genomics, and Algorithms and Data Structures for Strings. (Source: Lattes Curriculum)
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Gene fusion detection is essential for diagnosis, prognosis and treatment of cancer.Traditional methods for detecting gene fusions involve mapping short reads to a reference genome or transcriptome.However, these methods often yield a high number of false positives and require extensive filtering steps.Enhancing these methods with a targeted assembly subroutine mitigates this problem, but…
Advances in DNA sequencing technologies have enabled easy acquisition of genomes in computational environments. Methods for reconstructing phylogenies based on rearrangement events depend on a biologically meaningful notion of distance between genomes that can be computed efficiently. Several distance models and metrics have been developed over the years to achieve these goals, among whic…
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