CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Médicas (FCM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Medicina from Universidade Federal do Maranhão (2016) and doctorate at PhD in Biological Sciences from University of Reading (2021). (Source: Lattes Curriculum)
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Type 2 Diabetes Mellitus (T2DM) is a chronic and epidemic disease with high socio-economical cost worldwide, leading to an increased risk of cardiovascular disease (CVD) and thromboembolic events. These processes are largely mediated by platelet activation and endothelial dysfunction. Current anti-diabetic therapies provide limited cardiovascular protection, suggesting that diabetic patie…
Diabetic patients have a high risk of macrovascular complications, which are the main causes of mortality in these individuals. Platelets are key players in thrombus formation and macrovascular complications in diabetic patients. From a pathophysiological point of view, platelets are activated when they encounter vascular collagen and other extracellular matrix proteins that become expose…
Prolonged hyperglycemia leads to the formation of advanced glycation end products (AGEs) that generate tissue damage in diabetes. In this sense, endothelial dysfunction and vascular stiffening become key components in cardiovascular events in diabetic patients. Both effects may be linked to proteins with a long half-life of the extracellular matrix (ECM), such as type I collagen, which wo…
The production of reactive oxygen species (ROS) leads to the oxidation of proteins that generate damage present in chronic diseases, such as cardiovascular diseases. An important component of cardiovascular diseases associated with exacerbated ROS production is platelet hyperactivity, found in patients with risk factors for ischemic events. Platelets are important to prevent excessive ble…
(Only some records are available in English at this moment)
Diabetes is a chronic and epidemic disease with high socio-economical cost worldwide, being characterized by increased risk of cardiovascular disease (CVD) and thromboembolic event. Upon endothelial dysfunction, platelets bind to endothelial cells to precipitate thrombus formation in a process that is not fully understood. Specifically, it is still unclear which surface proteins regulate …
| 1 / 1 | Ongoing grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 2 / 2 | Completed scholarships in Brazil |
| 7 / 7 | All research grants and scholarships |
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