Abstract
The first interaction between the SARS-CoV-2 and the human cells occurs between the protein S of the viral capside and the ACE2 receptors, the main targets being the organs and tissues that contain these receptors. Protein S cleavage is mediated by a host protease and is crucial to the infection process. Even a high expression of ACE2, successful cell entry by SARS-CoV-2 cannot be guaran…