Miguel Antonio Xavier de Lima

• Abstract

  In this plan, the appointed researcher will conduct the hodological study on the Edinger-Westphal nucleus and Suproculomotor region. The results of our tract-tracingstudies for the EWcp and SOM will provide important insights to understand theirputative functional roles, which will be investigated, as the second part of this project, with loss of function experiments using DREADD inactiva…

  Neural systems for risk assessment, a biomarker for anxiety, BP.PD

• Abstract

  We have recently shown that inactivation of the ventral part of the anteromedial thalamic nucleus (AMv) impairs the acquisition of predator-related contextual fear memory acquisition. We have further shown that cytotoxic lesions in medial prefrontal cortical areas (PFM) targeted by AMv (i.e., the prelimbic (PL) and anterior cingulate areas (ACA)) also impair the predator-related fear memo…

  Involvement of prefrontal cortex areas and their targets in fear memory processing: a study with drug and optogenetic techniques, BP.PD

• Abstract

  Previous studies from our laboratory showed that memory to predatory threats depends on a hypothalamic-thalamic path involving the dorsal premammillary nucleus and the ventral part of the anteromedial thalamic nucleus (AMv). Thus, it has been shown that cytotoxic lesions of the AMv interfere with the contextual, but not innate, responses to predatory threats. Connective data from our lab …

  Study of the cortical circuitry involved in contextual fear processing to predatory threat, BP.DD

(Only some records are available in English at this moment)