Abstract
In healthy adults, fetal hemoglobin (HbF) levels are residual, but in some circumstances, there may be a variation with higher levels (0.8 to 5%), and this condition is called hereditary heterocellular persistence of HbF. In sickle cell disease (SCD), the increased expression of HbF during adulthood can improve the clinical course of the disease and prolong the life expectancy of these pa…