CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has experience in Pharmacy, focusing on Pharmacy (Source: Lattes Curriculum)
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Previous studies in our research group have identified a series of isoindolone-containing compounds with selective and potent activity against T. b. rhodesiense, no cytotoxicity, and excellent metabolic stability, but low solubility. This last parameter is one of the limitations of the most potent compounds and needs to be improved. In addition, the molecular target of the phenotypically …
Chagas disease is characterized as a neglected tropical disease, caused by the parasite Trypanosoma cruzi, which affects about 8 million people worldwide. However, despite alarming rates, the treatment consists of only 2 drugs, benznidazole and nifurtimox, which have numerous adverse reactions, high toxicity, and limited efficacy in the chronic phase. Furthermore, given the limited intere…
Chagas disease is a neglected tropical disease, caused by the parasite Trypanosoma cruzi, which affects about 8 million people worldwide. However, despite alarming rates, the existing treatment consists of only 2 drugs, benznidazole and nifurtimox, which have adverse reactions, high toxicity, and limited efficacy in the chronic phase. Furthermore, given the limited interest of the pharmac…
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