Abstract
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by persistent production of antiphospholipid autoantibodies (aPL), which are anticardiolipin (aCL), anti-²2glycoprotein-1 (a²2GP1) or lupus anticoagulant (LA), responsible for generating a prothrombotic state through the activation of endothelial cells, monocytes, and platelets. This pro-thrombotic state brings vascula…